Veniven

 

AREA OF USE/INDICATIONS

It is used to relieve breathing by controlling acute inflammation associated with respiratory tract diseases and to reduce the clinical signs of acute mastitis in cattle.

 

USAGE AND DOSAGE

Pharmacological Dose: 1,4 mg/kg body weight (1 ml/35 kg) subcutaneously or intravenously in cattle.

 

Practical Dose:

 

Target Species	Body weight	Veniven Sol. For Inj.	Administration Route
Cattle	140 kg	4 ml	Subcutaneously / Intravenously

 

 

SPECIAL CLINICAL INFORMATION AND SPECIAL WARNINGS FOR TARGET SPECIES

 

In general, NSAIDs can increase the tendency to bleed, especially in sensitive animals, because they inhibit the activity of thromboxane synthase, one of the mechanisms involved in blood clotting. Although studies conducted on cats and dogs before and after surgery have yielded successful results, NSAIDs should be used before and after surgery by a veterinarian, taking into account the benefits and risks, due to their effects on gastrointestinal ulcers and blood clotting.

Follow aseptic and antiseptic rules when using the product. It should not be administered simultaneously or within 24 hours with another NSAID. Do not use the product if there is a color change.

For effective treatment of infection-related diseases, the causative agent of the disease should be identified and treated with an appropriate antimicrobial.

Clinical studies have shown that carprofen has antipyretic activity and, when used with an antimicrobial appropriate for the infectious agent in cattle with respiratory tract infections, provides significant improvement in respiratory function.

The specified doses should not be exceeded.

It should not be administered in cases of dehydration, hypovolemia, or hypotension, as it may cause renal toxicity.

Intravenous administration should only be performed intravenously and slowly. Administration should be stopped immediately if neurological and cardiovascular signs appear during administration.

Use in animals younger than six weeks and in elderly animals may pose additional risks. When administration to such animals is necessary, the dosage should be reduced and carefully monitored throughout the treatment period.

 

Use during pregnancy and lactation: Since there are no studies on its use in pregnant and lactating animals, it should not be used in animals during this period.

 

 

ADVERSE EFFECTS

In some cattle treated with the drug, nodules may form at the injection site without fever or pain. These nodules are related to the trauma caused by the needle and are seen in a small number of animals.   

 

 

DRUG INTERACTIONS

In clinical studies conducted in cattle, macrolides, tetracyclines, cephalosporins, and enhanced penicillin group antibiotics were also administered to animals treated with carprofen, and no side effects were observed.

As with other NSAIDs, carprofen should not be administered simultaneously with another veterinary medicinal product belonging to the NSAID or glucocorticoid class. NSAIDs bind to plasma proteins to a high degree and may compete with other drugs used concomitantly, thus their combined administration may cause toxic effects. They should not be mixed with other drugs (in the same syringe or infusion).

 

 

SYMPTOMS OF OVERDOSE, PRECAUTIONS AND ANTIDOTE

In clinical studies, no side effects were observed after administration of 5 times the recommended intravenous and subcutaneous dose. There is no specific antidote for carprofen overdose. However, as with other NSAIDs, general supportive treatment should be administered.

 

 

WITHDRAWAL PERIODS

Meat: 21 days for cattle.

Milk: 0 days.

 

 

CONTRAINDICATIONS

Do not use in animals with heart, liver, or kidney disease, those at risk of gastrointestinal ulceration or bleeding, those with abnormal blood cell counts (blood dyscrasia), or those known to be hypersensitive to the product.

 

 

GENERAL WARNINGS

Consult a veterinarian before use and if any unexpected effects occur. Keep out of reach of children and away from foodstuffs.

 

 

PRECAUTIONS TO BE TAKEN BY THE ADMINISTRATOR AND WARNINGS FOR VETERINARY SURGEON

Veniven Injection Solution should not be accidentally self-injected, and contact with the eyes and skin should be avoided. If contact occurs, the affected area should be washed thoroughly with water. The application should be performed in accordance with general aseptic rules using the necessary protective equipment. Individuals who are hypersensitive to any of the active or auxiliary ingredients should not come into contact with the drug. If sensitive individuals experience symptoms such as tachycardia, difficulty breathing, or swelling of the hands and face, they should seek immediate medical assistance and refer to the drug label and package insert. Do not eat, drink, or smoke while administering the product.

 

 

STORAGE CONDITIONS AND SHELF LIFE

Before and after opening, the product should be stored below 25°C, in the original packages, without being frozen or placed in the refrigerator. Protect from sunlight. Shelf life is 3 years. It should be consumed within 28 days after opening.

 

 

DISPOSAL AFTER USE AND WARNINGS FOR NON-TARGET SPECIES

Empty and used bottles should be disposed of in accordance with the local authority's regulations governing the disposal of such materials. Unused product should not be disposed of in wastewater or drainage systems.

 

 

COMMERCIAL PRESENTATION FORM

50 ml and 100 ml amber-colored glass vials with cardboard boxes.

 

PLACE AND CONDITIONS OF SALE

It is sold in pharmacies and veterinary clinics with a veterinarian's prescription. (VHP)

 

APPROVAL DATE OF LEAFLET: 08.02.2018

 

MARKETING AUTHORIZATION DATE AND NO: 08.02.1018 – 027/0087

 

MARKETING AUTHORIZATION HOLDER

Pİ FARMA İLAÇ SAN. VE TİC. A.Ş.

Malıköy Başkent OSB Mah. 26. Cad. No:34/A Sincan/Ankara-Türkiye

 

MANUFACTURER COMPANY

FDN İLAÇ SAN. ve TİC. LTD. ŞTİ.

Büyükkayacık OSB Mah. İnsu Sokak No:3 Selçuklu/Konya-Türkiye

 

Made in Turkiye