Belif

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Product Group	:	Vitamins
Pharmaceutical Form	:	Solution for Injection
Active Ingredient	:	Vit. B₁, Vit. B₂, Vit. B₆, Vit. B₁₂, D-panthenol, Niacin
Target Type	:	Cattle, Buffalo, Horse,, Calf, Heifer, Calves, Foal, Sheep, Goat, Lamb, Kid
Package Form	:	100-250 ml

For Animal Use Only

Composition - Pharmacological Properties
Indications – Usage
Undesirable Effects – Warnings

For Veterinary Use Only

BELİF

Solution for Injection

Veterinary Vitamin

COMPOSITION

It is a clear, orange-yellow colored, sterile solution containing 5 mg Vit. B₁, 2 mg Vit. B₂, 2 mg Vit. B₆, 4 µg Vit. B₁₂, 10 mg D-panthenol, 20 mg Niacin per ml.

PHARMACOLOGICAL PROPERTIES

Belif Solution for ınjection contains B complex vitamins.

Vitamin B₁ (Thiamin), it is phosphated by ATP to thiamine diphosphate in the human and animal body. This substance, which is the active form of thiamine and acts as an ATP donor, is an important coenzyme involved in the intermediary metabolism of carbohydrates in the body.

Vitamin B₂ (Riboflavin), forms prosthetic groups of numerous enzymes that are absolutely essential for the metabolism of carbohydrates, fats and proteins in all domestic animals.

Vitamin B₆ (Pyridoxin), the active derivatives pyridoxal-5-phosphate and pyridoxamine phosphate form the coenzyme moiety of a wide variety of enzymes involved in the absorption, metabolism and transport of amino acids.

Vitamin B₁₂ (Cyanocobalamin), methyl cobalamin and co-enzyme B12 are converted into active metabolites and are involved in a wide range of biological processes in the animal body. Thus, it plays an important role in epithelial cells, myelin synthesis and maintenance of integrity in neural tissues, and synthesis of some auxiliary enzymes including normal nutrition, development, blood formation, growth and proliferation of all cells, including.

D-panthenol, it participates in the composition of co-enzyme A and acetyl carrier protein, which are of decisive importance for the realization of a wide variety of tissue metabolic processes in domestic animals.

Niacin, it is converted into coenzymes composed of NAD and NADP, which act as co-factors in the multifaceted oxido-reduction systems that are essential for tissue respiration in all advanced organisms. These nicotinic acid-derived enzymes are hydrogen carriers.

Belif Solution for Injection, is rapidly and completely absorbed from the application sites aAfter intramuscular (I.M.) administration. They are transported to the liver bound to plasma proteins. They are metabolized mainly in the liver. Vitamins passing through the same organ are distributed throughout the body. They are largely excreted from the body as products of metabolism and in very low proportions in unchanged form.

USE OF AREA / INDICATIONS

It is used in food-induced indigestion, indigestion during the course of infectious diseases, anorexia, slow growth, antibacterial applications that cause disruption of the flora of the digestive system, parasitic outbreaks, as a supplement to the main treatment, in skin, muscle and nerve diseases caused by deficiency of vitamins in the formulation, in various stress situations, low efficiency and physical weakness.

USAGE AND DOSAGE

It is administered subcutaneously or intramuscularly.

Practicle Dose Table

Target Species	Administration Dose (ml)
Cattle, Buffalo and Horse	15 - 30 ml
Calf, Heifer	10 -15 ml
Calve, Foal	5 - 10 ml
Sheep, Goat	5 - 10 ml
Lamb, Kid	3 - 5 ml

In order to achieve the predicted effects in the target animal species and to fully resolve clinical signs, the drug is continued for as long as necessary, repeating the selected one-time treatment doses 1-2 times a day.

SPECIAL CLINICAL INFORMATION AND WARNING FOR TARGET SPECIES

Do not use intravenously.

ADVERSE EFFECTS

In rare cases of hypersensitivity reactions, adrenaline should be used.

DRUG INTERACTIONS

Belif is an aqueous solution prepared on the basis of a balanced and harmonious combination of 6 types of water-soluble vitamin active substances by dissolving them in an aqueous medium with a very narrow limited pH value using various co-solvents, dissolution facilitating agents and oxidation inhibiting auxiliary substances. There may be a risk of clouding and precipitation when mixed with other liquid medicines during the application phase due to its special formulation and pharmaceutical form. In particular, it should not be mixed with liquid drugs with alkaline pH and infusion fluids containing calcium. It should not be used together with neuromuscular blocking drugs, glucocorticoids and antihistamines.

WITHDRAWAL PERIODS

‘0’ days for meat and milk.

CONTRAINDICATIONS

Anaphylactic shock may rarely occur in parenteral administration of thiamine. Inject slowly and in case of anaphylactic shock, treat with adrenaline.

Use in pregnancy and lactation: It can be used in pregnant animals.

GENERAL WARNINGS

Consult your veterinarian before use and in case of an unexpected effect. Keep out of reach of children and foodstuffs.

STORAGE CONDITIONS AND SHELF LIFE

Store at room temperature (15˚C-25˚C) in the original package, protect from light. Shelf life is 2 years.

COMMERCIAL PRESENTATION FORM

Offered for sale in 20 ml, 50 ml, 100 ml and 250 ml amber colored glass vials with cardboard boxes.

PLACE AND CONDITIONS OF SALE